Hamed Shafaroodi Selected Research

Pentylenetetrazole (Metrazol)

1/2022	Opioidergic and nitrergic systems mediate the anticonvulsant effect of mefloquine and chloroquine on seizures induced by pentylenetetrazol and maximal electroshock in mice.
2/2020	Novel fused 1,2,3-triazolo-benzodiazepine derivatives as potent anticonvulsant agents: design, synthesis, in vivo, and in silico evaluations.
10/2018	Acute foot-shock stress decreased seizure susceptibility against pentylenetetrazole-induced seizures in mice: Interaction between endogenous opioids and cannabinoids.
4/2017	Novel derivatives of phthalimide with potent anticonvulsant activity in PTZ and MES seizure models.
3/2016	A role for ATP-sensitive potassium channels in the anticonvulsant effects of triamterene in mice.
1/2016	Creatine Revealed Anticonvulsant Properties on Chemically and Electrically Induced Seizures in Mice.
9/2015	The influence of ovariectomy on anti-convulsant effect of pioglitazone in mice.
7/2015	The effect of acute aripiprazole treatment on chemically and electrically induced seizures in mice: The role of nitric oxide.
1/2015	The Effects of Sub-Chronic Treatment with Aripiprazole on Pentylenetetrazole- and Electroshock-Induced Seizures in Mice: The Role of Nitric Oxide.
8/2014	The effects of coenzyme Q10 on seizures in mice: the involvement of nitric oxide.

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Hamed Shafaroodi Research Topics

Disease

23	Seizures (Absence Seizure) 01/2022 - 07/2010
10	Cholestasis 07/2010 - 02/2004
8	Ischemia 09/2020 - 09/2005
7	Edema (Dropsy) 01/2019 - 04/2006
5	Pain (Aches) 12/2022 - 04/2015
4	Inflammation (Inflammations) 02/2022 - 01/2011
4	Reperfusion Injury 04/2020 - 10/2017
4	Hypotension (Low Blood Pressure) 08/2006 - 02/2004
3	Multiple Sclerosis 08/2021 - 01/2020
3	Necrosis 08/2019 - 09/2005
3	Epilepsy (Aura) 11/2014 - 09/2010
3	Bradycardia 08/2006 - 09/2004
2	Spinal Cord Injuries (Spinal Cord Injury) 09/2022 - 04/2021
2	Neuroinflammatory Diseases 09/2022 - 11/2012
2	Wounds and Injuries (Trauma) 02/2022 - 02/2022
2	Cognitive Dysfunction 08/2021 - 09/2012
2	Peripheral Nervous System Diseases (PNS Diseases) 04/2021 - 01/2020
2	Sepsis (Septicemia) 02/2021 - 10/2015
2	Morphine Dependence 09/2020 - 09/2006
2	Body Weight (Weight, Body) 01/2020 - 07/2009
2	Bipolar Disorder (Manic Depressive Psychosis) 10/2017 - 07/2010
2	Stroke (Strokes) 01/2016 - 11/2012
2	Fibrosis (Cirrhosis) 11/2015 - 06/2008
2	Traumatic Brain Injuries (Traumatic Brain Injury) 11/2012 - 09/2012
2	Liver Diseases (Liver Disease) 07/2008 - 09/2005
2	Cardiac Arrhythmias (Arrythmia) 09/2005 - 09/2004
1	Spinal Cord Compression 09/2022
1	Diarrhea 02/2022
1	Asthma (Bronchial Asthma) 02/2022
1	Irritable Bowel Syndrome (Syndrome, Irritable Bowel) 02/2022
1	Hypersensitivity (Allergy) 02/2022
1	Mitochondrial Diseases (Mitochondrial Disease) 04/2021
1	Acute Kidney Injury (Acute Renal Failure) 02/2021
1	Migraine Disorders (Migraine) 04/2020
1	Neuralgia (Stump Neuralgia) 01/2020
1	Weight Gain 01/2020
1	Chronic Kidney Failure (Chronic Renal Failure) 01/2020
1	Gastroesophageal Reflux (GERD) 08/2019

Drug/Important Bio-Agent (IBA)

21	Pentylenetetrazole (Metrazol)IBA 01/2022 - 07/2008
16	Nitric Oxide (Nitrogen Monoxide)FDA Link 04/2020 - 12/2002
11	Anticonvulsants (Antiepileptic Drugs)IBA 01/2022 - 07/2010
8	Morphine (MS Contin)FDA LinkGeneric 11/2020 - 09/2010
7	CarrageenanIBA 01/2019 - 04/2006
7	Opioid Analgesics (Opioids)IBA 10/2018 - 09/2004
6	Pharmaceutical PreparationsIBA 08/2021 - 04/2006
6	salicylhydroxamic acid (SHAM)IBA 09/2015 - 12/2004
6	NG-Nitroarginine Methyl Ester (L-NAME)IBA 07/2015 - 09/2004
6	Naltrexone (ReVia)FDA LinkGeneric 07/2008 - 09/2004
4	Acetic Acid (Vinegar)FDA LinkGeneric 02/2022 - 04/2015
4	Aripiprazole (Abilify)FDA Link 01/2020 - 01/2015
4	Nitric Oxide Synthase (NO Synthase)IBA 01/2020 - 09/2005
4	pimagedine (aminoguanidine)IBA 07/2015 - 12/2006
3	Glatiramer Acetate (Copaxone)FDA Link 08/2021 - 01/2020
3	Neuroprotective AgentsIBA 04/2021 - 09/2012
3	Analgesics (Analgesic Drugs)IBA 01/2019 - 04/2015
3	CannabinoidsIBA 10/2018 - 02/2004
3	Atorvastatin (Lipitor)FDA Link 01/2016 - 04/2012
3	Pioglitazone (Actos)FDA Link 10/2015 - 04/2012
3	LithiumIBA 12/2010 - 09/2006
3	Celecoxib (Celebrex)FDA Link 03/2007 - 04/2006
2	Interleukin-10 (Interleukin 10)IBA 09/2022 - 02/2022
2	Therapeutic UsesIBA 09/2022 - 04/2021
2	N-Methylaspartate (NMDA)IBA 11/2020 - 07/2010
2	Dizocilpine Maleate (Dizocilpine)IBA 11/2020 - 07/2010
2	Volatile Oils (Essential Oils)IBA 09/2020 - 04/2015
2	Arginine (L-Arginine)FDA Link 07/2015 - 04/2012
2	Adenosine (Adenocard)FDA LinkGeneric 11/2014 - 09/2013
2	Adrenergic Receptors (Adrenergic Receptor)IBA 11/2014 - 10/2005
2	ConvulsantsIBA 09/2013 - 04/2012
2	AcidsIBA 01/2011 - 12/2006
2	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 09/2010 - 07/2010
2	Narcotic Antagonists (Opioid Antagonists)IBA 12/2006 - 12/2004
2	Opioid Peptides (Opioid Peptide)IBA 09/2005 - 02/2004
1	Formaldehyde (Formol)FDA Link 12/2022
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 09/2022
1	Azithromycin (Zithromax)FDA LinkGeneric 09/2022
1	CytokinesIBA 02/2022
1	Glutamic Acid (Glutamate)FDA Link 02/2022
1	Acetylcholine (Acetylcholine Chloride)FDA Link 02/2022
1	Proteins (Proteins, Gene)FDA Link 02/2022
1	leukotriene D4 receptor (cysteinyl leukotriene receptor)IBA 02/2022
1	montelukast (Singulair)FDA Link 02/2022
1	Mefloquine (Lariam)FDA LinkGeneric 01/2022
1	Chloroquine (Aralen)FDA LinkGeneric 01/2022
1	Antidepressive Agents (Antidepressants)IBA 08/2021
1	Brain-Derived Neurotrophic Factor (BDNF)IBA 08/2021
1	Anti-Bacterial Agents (Antibiotics)IBA 04/2021
1	Biomarkers (Surrogate Marker)IBA 02/2021
1	Reactive Oxygen Species (Oxygen Radicals)IBA 09/2020
1	Tryptamines (Triptans)IBA 04/2020
1	Sumatriptan (Imigran)FDA LinkGeneric 04/2020
1	Vincristine (Oncovin)FDA LinkGeneric 01/2020
1	NF-kappa B (NF-kB)IBA 01/2020
1	Proton Pump InhibitorsIBA 08/2019
1	CreatinineIBA 08/2019
1	Pantoprazole (Protonix)FDA LinkGeneric 08/2019

Therapy/Procedure

7	Ligation 02/2021 - 09/2004
2	Punctures 02/2021 - 10/2015
1	Surgical Instruments (Clip) 09/2022
1	Kidney Transplantation 01/2020